A study has found out that the women who are early risers have a low risk of developing breast cancer than those who woke up late. The researchers used Mendelian randomization technique to analyze genetic variants of three sleep traits- morning or evening preference (chronotype), sleep duration and insomnia.
Databases of more than 4 lakh women from two studies- UK Biobank study and Breast Cancer Association Consortium (BCAC) study were analyzed.
From the analysis of UK Biobank data, the researchers found out that the women with morning preference was associated with a lower risk of breast cancer than evening preference, whereas the association with sleep duration and insomnia symptoms lacked a significant evidence.
Similar observations were observed in BCAC analysis, protective effect of morning preference and harmful effect of longer sleep duration (more than 7-8 hours) on breast cancer. The evidence for insomnia symptoms was not consistent.
The study has future research potential in determining how the stress on our biological clock can be reduced.
Mr Vinod Arora, Principal Advisor, IGMPI
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